In recent years, the emergence of GLP-1 medications like Ozempic®, Wegovy®, and Mounjaro® has brought about a significant shift in the treatment of type 2 diabetes, offering a promising new avenue for weight loss. These medications, with their life-changing potential, have also been associated with an unexpected side effect known as “Ozempic Teeth.”
Whether you're using these medications for blood sugar management or weight loss, it's crucial to grasp their potential impact on more than just your weight—specifically, your oral health. This understanding can empower you to take proactive steps to protect your oral health.
What Are GLP-1 Medications?
GLP-1 receptor agonists are injectable medications that mimic a hormone to help lower blood sugar, reduce appetite, and support weight loss. While originally intended for diabetes treatment, they've gained popularity for helping people shed significant pounds—and often, improve overall health markers.
But with this new popularity comes a new trend in dentistry.
“We're seeing more patients taking GLP-1 drugs and suddenly developing dry mouth, cracked teeth, or gum issues,” says Dr. Marielaina Perrone, DDS, a cosmetic and general dentist in Henderson, NV. “These symptoms aren't always listed in the drug packaging, but the clinical connection is becoming harder to ignore.”
What Is “Ozempic Teeth”?
“Ozempic Teeth” is a term being used by both patients and providers to describe unexpected oral health challenges that may develop during or after GLP-1 treatment. These include:
Dry mouth (xerostomia)
Enamel erosion
Tooth sensitivity or fractures
Receding gums
Increased dental pain
Why Is This Happening?
Although research is still ongoing, experts like Dr. Perrone suggest there are several potential reasons for these dental issues:
1. Reduced Saliva Production
One of the side effects of these medications is nausea or appetite suppression, which may lead to dehydration and dry mouth—a condition that reduces the mouth's natural ability to protect teeth.
“Saliva isn't just for digestion—it protects your enamel, neutralizes acids, and washes away bacteria,” Dr. Perrone explains. “When saliva is diminished, your risk for decay and gum problems increases.”
2. Nutritional Gaps
Patients taking Ozempic or similar medications often eat less. While that can support weight loss, it may also unintentionally reduce vitamin and mineral intake, especially nutrients important for oral health, like calcium and vitamin D.
3. Rapid Weight Loss Stress
Dramatic weight loss or hormonal changes can cause shifts in the body's metabolic processes, possibly affecting bone density—including the jawbone that supports your teeth.
Real-Life Patient Perspective
Dr. Perrone recalls a patient in her 50s who started semaglutide (Ozempic) and returned to her dental office just a few months later with a cracked molar and severe tooth sensitivity.
“She hadn't changed her brushing routine, had no history of trauma or decay, and didn't grind her teeth,” Dr. Perrone shares. “We ruled out most other causes and linked her symptoms to new medication use.”
The patient's treatment plan included:
-Fluoride varnishes
-Nightguard for added protection
-Hydration guidance
-Prescription toothpaste to rebuild enamel
What Can You Do If You're Taking These Medications?
If you are currently using a GLP-1 drug like Ozempic, here are steps to protect your smile:
Stay well-hydrated throughout the day
Use fluoride-based products to strengthen enamel
Avoid acidic or sugary snacks and drinks
Discuss symptoms with your dentist
Maintain regular dental visits for cleanings and check-ups
Never stop medication without consulting your physician
“It's not about stopping treatment—it's about being informed and proactive,” Dr. Perrone advises. “When dentists and patients work together, we can prevent most complications before they start.”
Should You Be Worried?
It's important to note that severe dental side effects are not common among people using GLP-1 medications. However, if you do notice changes in your oral health after starting Ozempic or Wegovy, it's best to discuss it with your dentist for reassurance and guidance.
Your dental care provider can offer targeted strategies to counter dry mouth, monitor tooth structure, and ensure you maintain a healthy, confident smile while reaching your other health goals.
Final Thoughts
Ozempic and other GLP-1 medications are changing lives, but they may also be changing mouths. Understanding the potential risks and staying ahead of symptoms can protect oral health while reaping the benefits of modern medical treatments.
“Dental care isn't separate from the rest of your body,” says Dr. Perrone. “What's good for your health should also support your smile.”
About the Expert
Dr. Marielaina Perrone, DDS, is a highly experienced cosmetic and general dentist practicing in Henderson, Nevada. She focuses on smile makeovers, dental implants, and managing patients with complex medical histories. She is passionate about the oral-systemic connection and helping patients take control of their health through education and personalized care.
